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By: Alexandra Vamvakidou of PerkinElmer Informatics
We present an overview of the OmicsOffice Data Integration tool where researchers can quickly integrate and compare genomics results. Specifically, we will examine data from an Illumina RNASeq experiment and compare its ability to identify differentially expressed genes from Affymetrix microarray results
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By: Alexandra Vamvakidou of PerkinElmer Informatics
Animal studies are generally conducted for a longer duration, generally three to six months, and are conducted using multiple doses. The purpose of these studies is to determine target-organ toxicity, to determine the effects of prolonged dosing, and to help establish margins of safety for food additives and drugs. At the end of a study all animals are autopsied, with complete gross and microscopic examination of tissues. Complete blood chemistries are evaluated and an overall clinical assessment is made on each animal. These studies are usually conducted under the Good Laboratory Practices (GLP) guidelines